![]() ![]() Raynaud phenomenon also occurs in systemic lupus erythematosus, dermatomyositis, Sjögren syndrome, and granulomatosis with polyangiitis. Ulceration of the fingertips may occur if vasospasm is severe. Systemic sclerosis (a systemic form of scleroderma) is the most likely connective tissue disease to present with Raynaud phenomenon, especially the CREST syndrome form: calcinosis, Raynaud, (o)esophageal dysfunction, sclerodactyly, telangiectasis. What causes secondary Raynaud phenomenon? Connective tissue diseasesĬonnective tissue diseases are believed to be due to disordered regulation of the immune system. The underlying connective tissue disease may not be apparent when Raynaud phenomenon first occurs. Patients with secondary Raynaud phenomenon often have the symptoms of an associated condition (see below) or are on medication that can cause Raynaud phenomenon as a side effect. Individuals often recall cold intolerance dating back to childhood. ![]() It usually starts under 25 years of age and is five times more common in women than in men. Primary Raynaud phenomenon is about twice as common as the secondary form. Secondary Raynaud phenomenon has the same symptoms due to an identifiable cause or condition.It as an exaggeration of the normal response of the circulation to cold. It affects at least one in five young women, and is less common in males, children and older individuals. This is not associated with any other conditions. Primary Raynaud phenomenon, also known as Raynaud Disease.Raynaud phenomenon can be divided into two main types: Raynaud phenomenon is an episodic reduction in the blood supply to the fingers, toes, or nipple occurring mainly in response to cold (vasospastic disease).
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